We consider the framework of uplink transmission and interference constraint for new system model to provide multiple access scheme for fifth generation (5G) wireless communications. In particular, such considered system contains normal cellular users deploying a non-orthogonal multiple access (NOMA) scheme and underlay device-to-device (D2D) users deploying traditional orthogonal multiple access (OMA). Such potentials motivate us consider uplink in cellular network in which the base station (BS) is required to fulfill two NOMA users’ diverse quality of service (QoS) requests under location arrangement with nearby D2D user pair. With regard to enhanced successive interference cancellation (SIC) scheme, the BS still performs the signal detection of NOMA users based on the decoding order and even though existence of an extra interference from D2D user pair. In term of quality evaluation, the ergodic capacity and outage probability are two underlying metrics need be investigated systematically. As important results, detailed derivations are provided in a scenario that considering coexistence of D2D users and NOMA users. As extended scenario, multiple antenna NOMA users exhibit improved performance and the related comparisons are provided. Finally, simulations in various scenarios are conducted to corroborate the precision of the mathematically derivations and to confirm potential of deployment in NOMA with SIC operation.